1/10/2023 0 Comments Shot put and discus shoes![]() Amazon has topped every other online platform in case of authenticity and trust issues. Therefore, by searching on Reddit, it becomes easier to know about shoes for shot put and discus more as all of the comprehensive details of it are available, be it the function, size, or brand.Įven if you are looking for any specific details for your shoes for shot put and discus, the online reviews can get you covered. Almost all types of product threads are available if it isn’t too rare of a kind. You can also lookup other online selling platforms and go to their review sections to get a good idea about your product.Īnother useful way of finding authentic reviews is Reddit threads.Usually, people around the globe seek help for a product review or share their thoughts on how that product is as a whole. Instead, just open your browser and type in the name of your product, and you’ll find a variety of platforms selling it.Īmazon tops the priority list as it has become one of the best online selling platforms around the world. That is why reviews matter so much in today’s marketing strategies, as people love to buy the facts used as practical examples by users.ĭon’t worry you don’t have to knock door to door to ask if the shoes for shot put and discus is worth buying or not. Our first step of research start from ‘Word of Mouth’. Usually, before buying anything, we often consider having opinions from others who have purchased it before. Now that's hammering the competition.Take these Factors into Consideration Before Purchasing Your shoes for shot put and discus But the gold medal clearly goes to the hammer throw, hurled with enough energy to power a light bulb for a full minute. And squeezing into second with one more second of illumination is the shot. In third is the discus, powering a light bulb for 15 seconds. So in fourth place, a javelin thrown the world-record distance has enough energy to power a 50-watt light bulb for eight seconds. So which one- the hammer, javelin, discus or shot- gets thrown with the most energy? Ignoring trivial things like air resistance and lift, we can figure out roughly how much energy each implement has just by knowing its weight and how far it gets thrown. It still has the longest world record, but the javelin is considerably lighter than the other implements. I mean, in the 1980s, they had to redesign the javelin to make it harder to throw, because athletes were starting to lob it farther than the entire length of a stadium and into the stands. Now, Olympians can toss all of these things pretty far. The discus, as you may know, is basically a four-pound Frisbee. The hammer and shot each weigh 16 pounds, which is two or three babies' worth of iron, either swung around at the end of a chain or hurled with brute strength. Let's have a face-off of the most burly Olympic hurling events- the hammer throw, javelin, discus, and shot put. SpaceNext50 Britannica presents SpaceNext50, From the race to the Moon to space stewardship, we explore a wide range of subjects that feed our curiosity about space!.Learn about the major environmental problems facing our planet and what can be done about them! Saving Earth Britannica Presents Earth’s To-Do List for the 21st Century. ![]() Britannica Beyond We’ve created a new place where questions are at the center of learning.100 Women Britannica celebrates the centennial of the Nineteenth Amendment, highlighting suffragists and history-making politicians.COVID-19 Portal While this global health crisis continues to evolve, it can be useful to look to past pandemics to better understand how to respond today.Student Portal Britannica is the ultimate student resource for key school subjects like history, government, literature, and more.This Time in History In these videos, find out what happened this month (or any month!) in history.#WTFact Videos In #WTFact Britannica shares some of the most bizarre facts we can find.Demystified Videos In Demystified, Britannica has all the answers to your burning questions.Britannica Explains In these videos, Britannica explains a variety of topics and answers frequently asked questions.Britannica Classics Check out these retro videos from Encyclopedia Britannica’s archives.
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1/10/2023 0 Comments Toothfairy day![]() However, there are certain unwritten rules on how to raise your son or daughter to become a useful member of society. The fact that no baby comes with a manual makes the monumental task of parenting even more challenging. Parenthood is one of life’s most demanding jobs. Make Up Excuses If The Fairy Doesn’t Come Say Something About What the Fairy Plans to Do With the Tooth Mention Something About Good Oral/Dental Hygiene They got so many sprinkles that they had tummy aches and had to go home for the night until they felt better.Ģ5- She texted us to tell us that she was running a day late and would be coming sometime today. Let’s make her a sign tonight that leads her to your room.ġ8- Oh! Last night was the night that the movie “Tooth Fairies Forever” was on TV, so she probably took a night off to hang out with her friends.ġ9- She tried to use a drone to fly over & drop the dollar, but it didn’t work.Ģ0- She tried to convince the stork to switch jobs with her for the night, but he wouldn’t.Ģ1- She broke her magnifying glass (the one that she uses to search for teeth).Ģ2- She asked her brother to do it, but he forgot.Ģ3- Her mom made her stay home to clean her room.Ģ4- She ran into another tooth fairy on her way and they decided to go out for ice cream. That explains the sparkles that I saw in the hallway when I got up last night.ġ7- I thought that I saw her in our bedroom last night, instead of yours. She must have been feeling sick and gone home so she wouldn’t spread her germs.ġ6- She may have heard me walking around and decided she would try again another night. If you come out of bed before 7:00 and the tooth fairy doesn’t usually come until really early in the morning.ġ4- I found the thermometer out, so that explains it. She probably had to leave to wash her wings.ġ2- Santa needed her help with one of his Elves (he bit a carrot too hard and hurt his tooth!)ġ3- You woke up too early. If fairies get syrup on their wings, they can’t fly well so they have to call their friends to come and get them. ![]() On those nights, we have to remember these 25 things…ġ- He was in a meeting with the Easter Bunny and their meeting went over.Ģ- It was raining where she was and she couldn’t see in the rain.ģ- Her wing was hit by a raindrop and she had to go home to let it dry.ĥ- Her tooth fairy bag was too full of teeth and she had to go home to empty it.Ħ- Her money fell out and dropped into a lake and she couldn’t get it.ħ- She ran out of ‘fairy dust’ and couldn’t fly.Ĩ- She saw a squirrel that was stuck in a tree and needed to help him.ĩ- She heard you waking up and had to leave before you saw her.ġ0- The dog/cat saw her so she had to leave until the next night.ġ1- I found the pancake mix out and someone spilled syrup (I already cleaned it up). Sometimes she even forgets to come all together. Then we put the tooth in their Tooth Fairy Pillow (yes, we have to do this because more than once, the tooth has been lost and the Tooth Fairy just had the hardest time finding it!) The Night Before the Tooth Fairy or Loose Tooth (easy reader – they can read to me) or Peppa Pig: The Tooth Fairy. ![]() The night before the Tooth Fairy comes, we sit down and read one of these three Tooth Fairy books: When the kids wake us up to tell us that the tooth fairy forgot to come last night – we need to be quick on our feet to think of a reason why. Our tooth fairy usually comes and leaves a cute little note that smells like perfume and has fancy handwriting, but sometimes she just forgets! I guess we shouldn’t be too surprised- during December, our Elf on the Shelf forgot to move all the time! 1/10/2023 0 Comments Calik fifa 22![]() Among Goalkeepers Jan Oblak has the highest FIFA.ĬDM players usually help the defenders in their team for defenses. Finally there will be more 85-rated players for sure but then the list would become the Top. List of Top 100 Goalkeepers on FIFA 21 A Goalkeeper GK is a designated player directly in charge in preventing the opposing team from scoring by blocking or intercepting opposing shots on goal.įIFA 22 Rating Prediction FC Barcelona. FIFA 21 FIFA Mobile Gameplay CONMEBOL Libertadores Unrivaled Authenticity Cover Athlete VOLTA FOOTBALL FIFA Ultimate Team Career Mode Pro Clubs Tips Tricks Accessibility Features Item Types Ratings Hub Top 100 Players ICONS Team Of The Year FIFA.įind out who the Top 100 Center Defensive Midfielders on FIFA. EA Sports announced they’ve locked the price of Turkish footballer Ahmet Calik’s card in FIFA 22 after the player tragically passed away in a car accident. Find out how good Ahmet Çalik is in FM 22 including Ability & Potential ability. ALIK, RONALDO, LINGARD.This video is about latest transfers. Mantan klubnya, Galatasaray, dan klub yang dibelanya sebelum meninggal, Konyaspor, telah mengungkapkan bela sungkawa atas kepergian tragis bek tersebut. FIFA 22 NEW CONFIRMED TRANSFERS & RUMOURS FT. Until then enjoy these profiles of the best seven players in this years game followed by a rundown of the top 100 FIFA 21 ratings list. - Pemain tim nasional (timnas) Turki Ahmet Calik dikabarkan meninggal dunia dalam usia 27 tahun akibat kecelakaan mobil pada Selasa, demikian laporan dari Reuters. FC Bayern Munich got some upgrades because in FIFA 21 they were simply rated way too bad. FIFA Non FIFA Season Country M S G M S G 2017. The players height is 184cm 60' and his weight is 77kg 170lbs. Ahmet Çalk FIFA 22 has 2 Skill moves and 4 Weak Foot, he is Right-footed and his workrates are Low/High. He is 27 years old from Turkey and playing for Konyaspor in the Turkey Süper Lig (1). Hot Fifa 22 French Players Ratings In Fut 22 Predictions Samagame FIFA 22 Leaks - All The Rumors.įifa 22 ratings top 100. His potential is 71 and his position is CB. A Center Defensive Midfielder CDM is a midfield player with a primarily defensive role. alk represented Turkey at the 2013 UEFA U-19 Championship and 2013 FIFA U-20 World Cup. 1/10/2023 0 Comments Right triangle similarity theoremThey are the same size, so they are identical triangles. The two equilateral triangles are the same except for their letters. Side F O is congruent to side H E side O X is congruent to side E N, and ∠ O and ∠ E are the included, congruent angles. Both ∠ O and ∠ E are included angles between sides F O and O X on △ F O X, and sides H E and E N on △ H E N. Notice that ∠ O on △ F O X corresponds to ∠ E on △ H E N. To make your life easy, we made them both equilateral triangles. You cannot compare two sides of two triangles and then leap over to an angle that is not between those two sides. The included angle refers to the angle between two pairs of corresponding sides. If the ratios are congruent, the corresponding sides are similar to each other. You can establish ratios to compare the lengths of the two triangles' sides. Their comparative sides are proportional to one another their corresponding angles are identical. ![]() Triangles are easy to evaluate for proportional changes that keep them similar. You look at one angle of one triangle and compare it to the same-position angle of the other triangle. The three theorems for similarity in triangles depend upon corresponding parts. Even if two triangles are oriented differently from each other, if you can rotate them to orient in the same way and see that their angles are alike, you can say those angles correspond. In geometry, correspondence means that a particular part on one polygon relates exactly to a similarly positioned part on another. These three theorems, known as Angle - Angle (AA), Side - Angle - Side (SAS), and Side - Side - Side (SSS), are foolproof methods for determining similarity in triangles. Similar triangles are easy to identify because you can apply three theorems specific to triangles. An equilateral triangle with sides 21 cm and a square with sides 14 cm would not be similar because they are different shapes. You could have a square with sides 21 cm and a square with sides 14 cm they would be similar. In geometry, two shapes are similar if they are the same shape but different sizes. This is an everyday use of the word "similar," but it not the way we use it in mathematics. Mint chocolate chip ice cream and chocolate chip ice cream are similar, but not the same. ![]() Similar triangles are triangles with the same shape but different side measurements. Similarity in mathematics does not mean the same thing that similarity in everyday life does. Similar Triangles (Definition, Proving, & Theorems) 1/10/2023 0 Comments Shadow boxIt’s sometimes nice to make a frame from cardstock. Other times, when shipping a gift, I may not want to worry if the glass will break or add to the weight of my package. Sometimes I’ve found it difficult to find Shadow Box frames in stock as they’ve become so popular. Please see my Privacy Policy for full details. How To Slice And Weld In Cricut Design SpaceĪlso please do pop over to Instagram, and give me a follow and if you make a project tag me! I love seeing everyone else’s makes and chatting crafting.This post may contain affiliate links.Tips And Advice For Using Your Woodland Alphabet SVG/PNG, Free Download. More Christmas Holiday Craft Ideas And Projects Now stick some sticky pads to the back of the box frame and position you woodland scene. Keep working though the layers until you have built up the whole Woodland Christmas shadow box. Now apply double sided tape to the back of layer 2, flip this over and attach to the back layer. Starting at the back turn the back layer over. Start by lining up all the layers, group them together and place face downwards on the craft table. If you have any problems cutting check the mat, pressure and material settings as generally this is where the problem will lie. If your cutting mat looses its stickiness this will affect the quality of cut. Also make sure your mat is in good condition, this is vital for cutting intricate cuts.Īdditionally, set the material and cut pressure correctly to match whatever materials you’re cutting to guarantee a clean cut. If you are using double sided glitter I find it helps to also secure it with strong masking tape. Use a brayer to adhere the card-stock to your cutting mat. Tips For Cutting Your Files With A Cricut Maker I find it helps me pick out my card stock and colour my layers in design space accordingly. When you are ready to send your Christmas Shadow Box SVG files too cut, arrange your colours. Once grouped together you can move and size the project as a whole to the size you require. Once they do, select all, right click and group them together. Now size all of your woodland layers to ensure they all line up together. I aways use my Cricut cutting mat to do this, as I find it translates to design space easily. Next measure the internal area of you shadow box frame. Start by uploading all of your Christmas Woodland SVG files to Cricut Design Space. Here’s how you upload the files to Cricut Design Space. If you are already a subscriber check the members area under Christmas projects and the shadow box is ready for you there.ĭo make sure the pop-up blocker is turned off, Also if the email doesn’t arrive check your spam folder. How To Get My Christmas Shadow Box SVG To Use With Cricut, Glowforge Or Silhouette?Ĭlick the image below to get your free downloadable Woodland Christmas Shadow Box SVG/ PNG files and follow these instructions to add to Cricut Design Space. However, don’t forget to turn off any pop up blockers, also if your email doesn’t come through check your spam folder. Brayer ( This is my favourite tool ever, essential for cutting card).Box Frame, I used a 10×10, you can pick this up cheaply at Ikea or Amazon. ![]() 7 layers of card stock, I used both plain card stock and glitter card stock to create a dimensional effect.Tips And Advice For Using Your Woodland Alphabet SVG/PNG, Free Download.įree Woodland Christmas Shadow Box SVG And Tutorial You will need.More Christmas Holiday Craft Ideas And Projects.Tips For Cutting Your Files With A Cricut Maker.How To Get My Christmas Shadow Box SVG To Use With Cricut, Glowforge Or Silhouette?.Free Woodland Christmas Shadow Box SVG And Tutorial. 1/10/2023 0 Comments Farkle mcbrideIt has been marketed commercially since 1996 under the brand name Pocket Farkel by Legendary Games Inc. Whats a boy to do when his mother is a trapeze artist, she practices in the living room, and all he wants to do is watch TV with his friends? Celebrity authors are often horrible, but John Lithgow is a welcome exception. ![]() But he's never satisfied: Something is missing. Farkle can only marvel how accurately Riley has read his mind. A new virus had been discovered followed by the birth of hybrid children - half-animal babies. In the book, Farkle McBride is a musical prodigy that learns to Stores One listen to Farkle & Friends confirms what anyone who caught an episode of TV's 3rd Rock from the Sun might've suspected: Not only is John Lithgow a born entertainer, the kind who gives off a great big whiff of Broadway no matter what stage he's tripping across, he's also curiously more kid than grown-up. The actor, who also performs children's songs, told his publisher Simon & Schuster the Farkle story was originally a piece he sang for kids. McLain, Ember - From the animated TV series Danny Phantom (2004). He plays the violin, the flute, the trombone, and the drums with incredible skill, but he is never satisfied. Choose the version you want to try and click on the box/guy. Young Farkle McBride is a musical genius: He plays the violin, the flute, the trombone, and the drums with incredible skill. That's now how children (or anyone) should be treating possessions. Level E- The Mouse - ReadingPlus: The Mouse 1. He starred in the HBO television series Eastbound & Down, Vice Principals, and The Righteous Gemstones, also co-creating the former two with frequent collaborator Jody Hill while creating the latter himself. John Lithgow is the New York Times bestselling author of I Got Two Dogs Mahalia Mouse Goes to College Marsupial Sue Presents: The Runaway Pancake Im A Manatee Micawber Marsupial Sue The Remarkable Farkle McBride and Carnival of the Animals.An award-winning actor, he has starred on stage, film, and television. Vicari, who has served as board liaison to the department for more than 41 years, said he also supported McBrides appointment. ![]() Young Farkle McBride is a musical genius. His longest work, The Ring Cycle, is four operas meant to be performed together over four days. ![]() He talks about what kinds of foods they eat. By age 16, he was writing musical compositions. McBride, Farkle - From The Remarkable Farkle McBride (children's book by John Lithgow), 2000. Daniel Richard McBride is an American actor, comedian, producer, and writer. I didnt entirely understand the wordplay, but I still thought it was hysterical. He wanted to be the greatest player ever he wanted to be perfect. (Ages 3 - 10) How does someone become a conductor? McCall, Erin - From the TV show Tracey Takes On (1997). Its origins as a folk game are unknown, but the game dates back to at least the mid 1980s. Reply Farkle chooses to assume that she meant him, and hopefully speculates that he may now be part of the story. He has been the recipient of numerous accolades, including two Golden Globe Awards, six Primetime Emmy Awards, three Screen Actors Guild We love Micawber and The Remarkable Farkle McBride and Im a Manatee. Farkle, or Farkel, is a dice game similar to or synonymous with 1000/5000/10000, Cosmic Wimpout, Greed, Hot Dice, Squelch, Zilch, or Zonk. They build up "hands", such as 3 of a kind, straights, etc, and score. If you score NOTHING on that throw, you "FARKLE", and lose all your points for that round. ![]() Visit him online at part I object to is that after he tried out each instrument, he threw it away. Payne lives with his wife and children in Cincinnati, Ohio. He teaches at the Columbus College of Art & Design, where he is the chair of the Illustration Department. Payne has illustrated more than a dozen picture books, including the New York Times bestselling Mousetronaut by astronaut Mark Kelly the Texas Bluebonnet winner Shoeless Joe & Black Betsy, written by Phil Bildner and the New York Times bestsellers The Remarkable Farkle McBride and Micawber, both by John Lithgow. He performs concerts across the country and has recorded the CDs Farkle and Friends, Singin' in the Bathtub, and The Sunny Side of the Street. An award-winning actor, he has starred on stage, film, and television. John Lithgow is the New York Times bestselling author of I Got Two Dogs Mahalia Mouse Goes to College Marsupial Sue Presents: The Runaway Pancake I'm A Manatee Micawber Marsupial Sue The Remarkable Farkle McBride and Carnival of the Animals. 1/8/2023 0 Comments Blasphemous hd![]() When Blast confronted him about it he said that he didn't mean to send hate his way when he kept calling him a cock sucking cunt. ![]() ![]() Basically, PSI made a video calling Blast a cunt and put up a link to his channel in the description from which PSI's fans sent hate comments. His reaction to the drama with psi syndicate contains a lot of lampshades to this.Whenever Maurice says that he'll put the link to the original video in the description below.Most of the time, when Maurice says that he'll edit something out.Blast is confident that he will never fall victim to this trope, because he has mentioned many times that he runs as far away from danger as possible. Black Comedy: His humor sometimes dips into this, especially with him being seen as a Memetic Molester.J andtheWomen) or the video of him being harassed at VidCon 2016 by a black supremacist who previously threatened to kill him and wished cancer upon his mother note what's especially bad is that his mother actually is a cancer survivor and you'll see that Blast can be genuinely scary when he's properly enraged. Beware the Nice Ones / Beware the Silly Ones: Although Blast is a nice and funny person, just look at any of Randy's pranks towards Blast on his channel (Dr.On a more comedic side, joking, or mentioning his apparent age, given that he is much younger than his appearance would suggest, up to and including stop flirting with an attractive girl because she thought that he looked in his thirties (He was 18 at the time!).Trolls qualify as well, especially ones who threaten the lives of his friends and family.Out-of-control children who disrespect their parents.More so when bullies refuse to acknowledge their wrongdoings and attempt to treat anyone calling them out as overreacting. Anyone in general who tries to target weaker, quieter people just to feel tough seem to really piss Blast off. Bullies really get on his nerves, due to having been bullied as a kid.Troublemakers who, when confronted on their dickery, claim that 'it was just a joke bruh!' Indeed, one of the few legitimate times BHD did 'edit something out' was when he cut himself off before belting out a "fuck you!" in response to watching a video of a pair of troublemakers using that excuse when caught.Stupid people tend invoke this reaction in him, as well as Boomerang Bigots.Arson, Murder, and Jaywalking: What got him his first criminal penalty was getting into a violent brawl (which was so graphic, that Blast had to lock the story behind Patreon), but what actually got him arrested and sent to jail for two months was, fittingly enough, jaywalking.Blast: Oh my god, boyfriend! I thought it was you! How was I supposed to know this dick wasn't yours? It tasted the same!. 1/8/2023 0 Comments Cici sixtyfour![]() The reason for termination listed by the company was differentiating opinions between the company and the group. On September 17, UPVOTE Entertainment released a statement revealing the exclusive contract they had with CICI had been terminated. I am currently doing all that I can to locate him/her now. 2019: Debut, contract termination with agency Cici nodded, still trying to catch her breath and hoping she wasnt looking as flushed as she felt. Context: CiCi SixtyFour is this early 2010s FNaF animator that suddenly disappeared without a trace in 2015. Just have some began to steal her art and add to your account. Bear with me for stealing art's Sabine's. On February 18, they revealed another new member, Kim Yejoon, through a dance cover video. Hello This account re-upload art's Cinnamon Cici/Cici SixtyFour/64. ![]() On January 26, 2019, UPVOTE Entertainment revealed their first trainee boy group UPVOTE BOYS, through a dance cover video, revealing also the first members Won, Sunghyun and Haneul. ![]() 1.2 2019: Debut, contract termination with agency Join Facebook to connect with Cici Sixtyfour and others you may know. See a Problem FNAFWhen a Dog Dies in a Movie (FNaF Vine Ep.1) 35 Cici sixtyfour ideas fnaf, cool drawings, five nights at freddys The Missing. 1/8/2023 0 Comments Clix setup![]() going out with friends or having a movie night). During weekends, it is ok to relax for a bit (ex. ![]() When you’re tired, it is ok to take a nap. Though I’m not encouraging people to lower down their high standards/expectations here, sometimes we just need to follow our bodies’ instructions. Looking back to last year, instead of putting my own well-being as the priority, finishing work was always the No.1 task. This kind of anxiety accumulation eventually led to my mental devastation. I blamed myself every time I couldn’t reach my high standard. I stayed up until 3:00 am a lot to write up papers and sacrificed countless weekends for work - my only goal was to get things done. I had an average GPA 3.85 in my sophomore year, as a social science major. It’s unavoidable to stay up late or have a really intense schedule in this case. I know it sounds hard when you have lots of work to do. I hope my advice is helpful for people who share similar experience as myself. I feel obligated to write down something, not only as a self-reflection, but also for everyone who has suffered. But there are people who never get a chance to see the bright world I see now. Thanks to my friends, family, and people who cared about me, luckily, depression finally left at the end of last semester. This best graphics card for fortnite is a great option if you want to save money on other gaming peripherals. This graphics card is on the lower end of specifications and budget. Cost Effective GPU for Fortnite Main Specifications:Īlthough it is an old friend, GTX 1050 Ti may not be able to compete with modern GPUs, but it will satisfy your Fortnite cravings without any problems. Radeon RX 580 GTS Black Edition is undoubtedly the top choice for budget gamers around the globe.
1/8/2023 0 Comments Keynote 177![]() unresectable or metastatic gastric, small intestine, or biliary cancer, who have disease progression on or following at least one prior therapy. ![]() ![]() advanced or recurrent endometrial carcinoma, who have disease progression on or following prior treatment with a platinum-containing therapy in any setting and who are not candidates for curative surgery or radiation ![]() KEYTRUDA as monotherapy is indicated for the treatment of the following MSI-H or dMMR tumours in adults with: treatment of unresectable or metastatic colorectal cancer after previous fluoropyrimidine-based combination therapy. first-line treatment of metastatic colorectal cancer KEYTRUDA as monotherapy is indicated for adults with MSI-H or dMMR colorectal cancer in the following settings: Microsatellite instability high (MSI-H) or mismatch repair deficient (dMMR) cancers KEYTRUDA as monotherapy is indicated for the adjuvant treatment of adults with renal cell carcinoma at increased risk of recurrence following nephrectomy, or following nephrectomy and resection of metastatic lesions (for selection criteria, please see section 5.1). KEYTRUDA, in combination with lenvatinib, is indicated for the first-line treatment of advanced renal cell carcinoma in adults (see section 5.1). KEYTRUDA, in combination with axitinib, is indicated for the first-line treatment of advanced renal cell carcinoma in adults (see section 5.1). KEYTRUDA as monotherapy is indicated for the treatment of recurrent or metastatic head and neck squamous cell carcinoma in adults whose tumours express PD-L1 with a ≥ 50% TPS and progressing on or after platinum-containing chemotherapy (see section 5.1). KEYTRUDA, as monotherapy or in combination with platinum and 5-fluorouracil (5-FU) chemotherapy, is indicated for the first-line treatment of metastatic or unresectable recurrent head and neck squamous cell carcinoma in adults whose tumours express PD-L1 with a CPS ≥ 1 (see section 5.1). Head and neck squamous cell carcinoma (HNSCC) KEYTRUDA as monotherapy is indicated for the treatment of locally advanced or metastatic urothelial carcinoma in adults who are not eligible for cisplatin-containing chemotherapy and whose tumours express PD-L1 with a combined positive score (CPS) ≥ 10 (see section 5.1). KEYTRUDA as monotherapy is indicated for the treatment of locally advanced or metastatic urothelial carcinoma in adults who have received prior platinum-containing chemotherapy (see section 5.1). KEYTRUDA as monotherapy is indicated for the treatment of adult and paediatric patients aged 3 years and older with relapsed or refractory classical Hodgkin lymphoma who have failed autologous stem cell transplant (ASCT) or following at least two prior therapies when ASCT is not a treatment option. Patients with EGFR or ALK positive tumour mutations should also have received targeted therapy before receiving KEYTRUDA. KEYTRUDA as monotherapy is indicated for the treatment of locally advanced or metastatic non-small cell lung carcinoma in adults whose tumours express PD-L1 with a ≥ 1% TPS and who have received at least one prior chemotherapy regimen. KEYTRUDA, in combination with carboplatin and either paclitaxel or nab-paclitaxel, is indicated for the first-line treatment of metastatic squamous non-small cell lung carcinoma in adults. KEYTRUDA, in combination with pemetrexed and platinum chemotherapy, is indicated for the first-line treatment of metastatic non-squamous non-small cell lung carcinoma in adults whose tumours have no EGFR or ALK positive mutations. KEYTRUDA as monotherapy is indicated for the first-line treatment of metastatic non-small cell lung carcinoma in adults whose tumours express PD-L1 with a ≥ 50% tumour proportion score (TPS) with no EGFR or ALK positive tumour mutations. KEYTRUDA as monotherapy is indicated for the adjuvant treatment of adults and adolescents aged 12 years and older with Stage IIB, IIC or III melanoma and who have undergone complete resection (see section 5.1). KEYTRUDA as monotherapy is indicated for the treatment of adults and adolescents aged 12 years and older with advanced (unresectable or metastatic) melanoma. Date of first authorisation/renewal of the authorisation
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